Eng Kiang Lee

Incidence of CAUTI in a new integrated ICU/HD in Singapore over 1 year

Abstract Hospital-acquired infection worldwide has been associated with significant mortality and morbidity and unfortunately catheter-associated urinary tract infection (CAUTI) is known to be one of the commonest hospital-acquired infections. A retrospective study was done to determine the incidence of CAUTI in the Intensive Care Unit/High Dependency (ICU/HD) in Ng Teng Fong General Hospital (NTFGH) since […]

Vijo Poulose, Jansen Koh, Tay Tunn Ren, Wong Hang Siang, Ian Wee, Hannah Hsien Hwei, Kam Jia Wen

A randomized pilot study of parenteral glutamine supplementation in severe sepsis

Abstract Purpose: Glutamine depletion can occur in critically ill patients and parenteral glutamine supplementation can have beneficial effects on critically ill patients by preserving gut barrier and improving immune function. We wanted to examine the effect of glutamine supplementation in a cohort of severe sepsis patients admitted to a hospital in South East Asia. Design: […]

Rujipat Samransamruajkit, Kantara Saelim, Sumalee Hantragool, Jitladda Deerojanawong, Suchada Sritippayawan, Nuanchan Prapphal

A comparison of NSS vs balanced salt solution as a fluid resuscitation and impact of fluid balance on clinical outcomes in pediatric septic shock

Abstract Septic shock is a common condition affecting children worldwide. Initial resuscitation with crystalloid fluid is the first step in treatment of septic shock. However, there is increasing concern about side effects of using normal saline. Our objective was to compare the effectiveness of balanced salt solution vs 0.9% normal saline solution (NSS) on decreasing […]

Omar Alberto Venegas Gurrola, Omar Uriel Sánchez Alba, María Isabel Solís Gamboa, Goretti Monserrat Rodríguez Delgado

A 20-year-old woman with spinal cord injury without radiological abnormalities (SCIWORA)

Abstract Spinal cord injury without radiological abnormalities (SCIWORA) has been defined as a direct trauma to the spinal cord, with no radiological or tomographic abnormalities, although there is a deficit, whether motor, sensory or both. (1) To establish the final diagnosis, shock, obstetrical complications, penetrating trauma to the spine and congenital malformations should be excluded. […]

Tadashi Kaneko, Keiji Uezono, Ryuichi Karashima, Shinsuke Iwashita, Hiroki Irie, Shunji Kasaoka

Factors contributing to the accuracy of initial screening values measured by noninvasive spectrophotometric hemoglobin monitoring in an Emergency Department

Abstract Objective: Spectrophotometric hemoglobin (SpHb) monitoring is a new noninvasive technology for measuring hemoglobin (Hb). However, few studies have assessed the usefulness of the initial screening SpHb values, especially when measured in an Emergency Department. In this study, we examined the correlation between the initial screening SpHb values and laboratory-measured hemoglobin (Hb) concentrations. Design: This […]

Ying Tung Sia, Pierre Laurencelle

Portal venous gas entrapment secondary to mesenteric ischemia after withdrawal of intra-aortic balloon pump: A case report with a rare ultrasound image

Abstract After coronary artery bypass graft (CABG), mesenteric ischemia is a rare but dreadful complication with high mortality rates. Prophylactic use of intra-aortic balloon pump (IABP) is a common practice in patients with severe coronary artery disease awaiting CABG. During withdrawal of the IABP, there is a risk of dislodging atheromatous debris, thus causing peripheral […]

Saw Kian Cheah, Raha Abdul Rahman, Aliza Mohamad Yusof, Shereen Suet Ping Tang, Kamal-Bashar Abu Bakar

A fatal case of cerebral oedema and myocarditis associated with secondary dengue infection

Abstract Background: Secondary dengue infection (SDI), in the form of two sequential infections by different serotypes, will lead to severe dengue. Concomitant organ failure in particular cardiovascular (CVS) and central nervous system (CNS) carries further rise in the mortality rate. Case report: We report a confirmed SDI in a 27-year-old man who presented with hypovolemic […]

Alexander N. Osipenko, Alexei V. Marochkov

Blood plasma plasmalogens and fatty acids in multiple organ dysfunction syndrome

Abstract Introduction: Changes in fatty acid composition as well as in a level of blood plasma plasmalogens in cases of various pathological conditions are evidences of lipid metabolism disorders and can indicate their reasons and degree. The objective of this study was to analyze fatty acids and plasmalogens of blood plasma in patients with multiple […]

Dewi Yulianti Bisri, Zafrulah Arifin, Ike Sri Redjeki, Heni Listianto, Tatang Bisri

The effect of selective COX-2 inhibitor on blood glutamate in moderate traumatic brain injury

Abstract Head injury is the leading cause of death and disability in adolescence, children and the elderly. Post-traumatic brain damage is determined by combination of primary and secondary head injuries. Neuroinflammation is one mechanism of secondary brain injury. Selective cyclooxygenase (sCOX-2) inhibitors are drugs commonly used in treatment of postoperative pain but also possess an […]

Suryadi Nicolaas Napoleon Tatura, Priscilla Kalensang, Jose Meky Mandei, Sitti Wahyuni, Irawan Yusuf, Dasril Daud

Albumin level as a predictor of shock and recurrent shock in children with dengue hemorrhagic fever

Abstract Background: The severity of dengue hemorrhagic fever (DHF) can be seen from bleeding and plasma leakage manifestations. Albumin level is one of the markers of plasma leakage in dengue infection. Whether albumin can be used as a predictor of shock in DHF patients or of recurrent shock in dengue shock syndrome (DSS) patients still […]

Alberto Leguina-Ruzzi, Marcial Cariqueo, Ricardo Gálvez

Three years after the REDOXS study: What we have learned in the use of glutamine in ICU patients?

Abstract Critical illness has been associated with glutamine (Gln) plasma levels depletion and its supplementation is related with better outcomes. In 2013 the Reducing Deaths due to Oxidative Stress (REDOXS) study, showed that the supplementation of Gln to total parenteral nutrition was associated with higher mortality without conferring beneficial effects. These conclusions had a high […]

Stephanie Bustamante-Mata, Alamgir A. Khan, Joseph Varon, Salim Surani

Ureteral stents, sepsis and acute kidney injury: Iatrogenic imperfecta!

Case presentation A 62-year-old woman with a past history of placement of bilateral ureteral “JJ” stents, presented to the hospital complaining of fever, chills, abdominal pain, oliguria and was found to be hypotensive. She was admitted to the intensive care unit (ICU), with the diagnosis of sepsis secondary to a urinary source. Her white blood […]

Emmanuel Urquieta, Humayun Anjum, Sheila Zanoria, Joseph Varon, Salim Surani

Mediastinal lipoma with vascular compression

Case description A 56-year-old gentleman presented to the emergency department with shortness of breath and neck swelling of a couple of weeks duration. After a comprehensive physical examination and chest radiograph revealing an upper mediastinal abnormality, a computed tomography (CT) scan of the chest (Figures 1A and 1B) depicted a 8x7x5.7 cm mass with homogenous […]

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