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Lactic acid’s role in sodium hypertonic lactic solution as a neuroprotector measured from the level of ATP, MCT-1 and necrosis area in intracerebral hematoma rats model

Authors: Hamzah, Nancy Margarita Rehatta, Tatang Bisri, Siti Chasnak Saleh, Arie Utariani

Abstract Objective: To discover the role of hypertonic sodium lactate (HSL) as the energy source, which in turn will act as a neuroprotector, by measuring adenosine triphosphate (ATP) level, monocarboxylate transporter 1 (MCT-1) and the extent of the necrotic areas. Design: This was an experimental study that used randomized post-test only control group design. Setting: […]

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End-of-life care (EOLC) in Jordanian critical care units: Barriers and strategies for improving

Authors: Loai Abu Sharour, Maha Subih, Omar Salameh, Mohammad Alrshoud

Abstract Background: End-of-life care (EOLC) is a pivotal element of work in ICUs and for critical care nurses, thus, it is considered one of the top research priorities recently as number of admission ICUs increasing and high percentage of deaths also. Objective: This study was conducted to explore the obstacles of EOLC and strategies for […]

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Profile of children with rabies dog bites: Manado experience, Indonesia

Authors: Suryadi Nicolaas Napoleon Tatura, Elizabeth Clarissa Wowor, Priscilla Cantia Tatura-Kalensang, Meilany Duri, Tonny Homenta Rampengan

Abstract Background: Rabies is an infectious viral disease that is almost always fatal following the onset of clinical signs. Forty percent of all human rabies occur in children <14–year–old. In up to 99% of rabies virus is transmitted by dogs. Objective: To determine the mortality risk factor of children with rabies dog bites in Prof. […]

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Multivessel spontaneous coronary arterial dissection. Usefulness of angio-CT during follow-up

Authors: JF Garrido Peñalver, JH de Gea García, R. Jara Rubio, E. Pinar Bermúdez, JI Pascual de la Parte, S. Sánchez Cámara

Abstract Spontaneous coronary artery dissection (SCAD) is an uncommon but important cause of myocardial ischemia associated with a high mortality rate. Its aetiology, incidence and pathogenesis are still unknown. It is characterized by the presence of a hematoma and/or the separation of the different layers in the arterial wall, causing vessel lumen stenosis. The clinical […]

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Unusual presentation of tension pneumoperitoneum during endoscopic submucosal dissection of early gastric tumor

Authors: Phui Sze Au Yong, Gek Kim Sharon Ong

Tension pneumoperitoneum is a well-known but rare complication of upper gastrointestinal endoscopy. It is defined as the massive accumulation of air in the peritoneal cavity, which results in a sudden increase in intraabdominal pressure resulting in hemodynamic or ventilatory compromise. The presentation varies from intense abdominal pain and tenderness to imminent collapse. Download Attachments [...]

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Electrical cardiometry for non-invasive cardiac output monitoring in children with dengue hemorrhagic fever and shock in comparison between referral and non-referral

Authors: Ira Dharmawati, Andri Kurnia Wahyudhi, Intani Dewi Syahti Fauzi, Arina Setyaningtyas, Dwi Putri Lestari, Neurinda Permata Kusumastuti, Abdul Latief Azis

Abstract Objective: Shock in dengue hemorrhagic fever (DHF) is mostly caused by plasma leakage. Hemodynamic monitoring is essential for improving the quality of management and the outcome. We sought to find the hemodynamic profile of dengue hemorrhagic fever children with shock. Design: a cohort prospective study. Setting: Pediatric Intensive Care Unit (PICU) at tertiary general […]

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The effectiveness of a short training course for emergency medicine residents to confirm tracheal tube placement by ultrasound

Authors: Mohammad Afzalimoghaddam, Kamal Basiri, Seyedhossein Seyedhosseini-Dvarani, Farideh Bagheri, Ehsan Karimialavijeh

Abstract Objective: The present study aimed to evaluate the performance of tracheal ultrasound by novice emergency medicine residents after participating in a short training course. Methods: This was an observational prospective study conducted between July 2016 and September 2017 at three university-affiliated emergency departments in Tehran, Iran. Adult patients (over 18 years of age) who […]

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Fatal neck necrotizing fasciitis caused by hypermucoviscous Klebsiella pneumoniae

Authors: U Wen Yeap

Abstract Klebsiella pneumoniae is a gram-negative rod enterobacteria that is notorious for its role as carrier of extended spectrum beta-lactamase (ESBL) and its carbapenem resistant Enterobacteriaceae (CRE) species. However, hypermucoviscous Klebsiella pneumoniae is distinctly different from ESBL and CRE. We report a case of neck necrotizing fasciitis caused by hypermucoviscous Klebsiella pneumoniae in a 56-year-old […]

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Delirium in critically ill patients: incidence, risk factors and outcomes

Authors: Lavitha Vyveganathan, Azarinah Izaham, Wan Rahiza Wan Mat, Shereen Tang Suet Peng, Raha Abdul Rahman, Norsidah Abdul Manap

Abstract Objective: To determine the incidence, and evaluate the risk factors and outcomes of delirium in general Intensive Care Unit (ICU). Design: Prospective cross-sectional observational study. Setting: Teaching hospital in Kuala Lumpur, Malaysia. Patients and participants: Patients ages of 18 and above admitted for more than 24 hours in general ICU were recruited into the […]

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Dispatcher-assisted cardiopulmonary resuscitation improves the neurological outcomes of out-of-hospital cardiac arrest victims: a retrospective analysis of prehospitalisation records in Kumamoto City

Authors: Tadashi Kaneko, Hiromichi Tanaka, Keiji Uezono, Ryuichi Karashima, Shinsuke Iwashita, Hiroki Irie, Kazuo Nishioka, Shunji Kasaoka

Abstract Background: Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) is an effective tool for improving the outcome of out-of-hospital cardiac arrest (OHCA) by providing dispatcher assistance (DA) to bystander cardiopulmonary resuscitation (BCPR) and public access defibrillators (PAD). However, it is unclear whether DA-CPR improves the neurological outcomes of OHCA. In this study, we assessed the effectiveness of DA-CPR […]

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The successful treatment of severe aspiration pneumonitis with the combination of hydrocortisone, ascorbic acid and thiamine

Authors: Margot M. Gurganus, Paul E. Marik, Joseph Varon

Abstract Aspiration pneumonitis is a neutrophil mediated inflammatory pneumonitis following the aspiration of regurgitated gastric contents. This syndrome occurs most commonly in patients with depressed levels of consciousness such as drug overdose, seizures, and during anesthesia. Aspiration pneumonitis is the most common cause of anesthesia-related deaths. Aspiration pneumonitis may be clinically silent or present as […]

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The accuracy of SIRS criteria, qSOFA and SOFA for mortality suspected sepsis patient admitted to the Intensive Care Unit Dr. Hasan Sadikin General Hospital Bandung, January-December 2017

Authors: Tinni T. Maskoen, LS Philip, Indriasari, I. Fuadi

Abstract Objective: The high mortality rate found on infectious patients in the intensive care unit (ICU) calls for sepsis identification tools. Sepsis consensus introduced Systemic Inflammatory Response Syndrome (SIRS) criteria, quick Sequential Organ Failure Assessment (qSOFA) score, and Sequential Organ Failure Assessment (SOFA) score. This study aimed at comparing the accuracy and quality to discriminate […]

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