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Susumu Hirosako, Hirotsugu Kohrogi, Katsuyuki Sagishima, Keisuke Sakai, Yohei Migiyama, Hidenobu Kamohara, Hiroaki Kawano, Yoshihiro Kinoshita

Decision making of tracheostomy and extubation outcomes in mechanically ventilated patients evaluated by logistic regression and decision tree analyses

Abstract Background: Most studies determining the predictors of extubation outcomes in patients with mechanical ventilation have not included high-risk populations who avoid extubation and undergo tracheostomy. Objective: To evaluate predictors of extubation intolerance by analyzing patients regardless of whether extubation was attempted or not. Design: Retrospective cohort study. Settings: Mixed intensive care unit (ICU) of […]

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Ni Luh Kusuma Dewi, Yohanes WH George

Case report: central venous pressure-guided de-resuscitation in sepsis patients with fluid overload induced acute kidney injury

Abstract Background: Aggressive fluid resuscitation is commonly administered in septic patients as recommended by Surviving Sepsis Campaign. However, positive fluid cumulative balance resulting in fluid overload is correlated with various complications such as acute kidney injury, acute respiratory distress and delayed wound healing. Case report: This report presents four septic patients with fluid overload and […]

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Orivaldo Alves Barbosa, João Filho Araujo Ribeiro, Paola Lima Lemos

Status epilepticus caused by cerebral venous thrombosis in the puerperal period: case report and literature review

Abstract Status epilepticus (SE) caused by cerebral venous thrombosis (CVT) is rare in pregnancy and puerperium, with few cases described in literature. Seizures in pregnancy are usually due to previous epilepsy or pregnancy related disease, such as eclampsia, posterior reversible encephalopathy syndrome (PRES), reversible cerebral vasoconstriction syndrome (RCVS), eclampsia and thrombotic thrombocytopenic purpura (TTP). Due […]

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Wun Fung Hui, Winnie Kwai Yu Chan

Role of hemofilter with endotoxin adsorption capacity in management of septic shock

Abstract We reported an adolescent male with acute lymphoblastic leukemia who developed septic shock due to Klebsiella pneumoniae. Continuous renal replacement therapy using a hemofilter with endotoxin adsorption capacity was used to remove endotoxin and cytokines. The promising result suggested that this technique may be applied as an adjuvant therapy for treatment of septic shock. […]

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Eng Kiang Lee

Incidence of CAUTI in a new integrated ICU/HD in Singapore over 1 year

Abstract Hospital-acquired infection worldwide has been associated with significant mortality and morbidity and unfortunately catheter-associated urinary tract infection (CAUTI) is known to be one of the commonest hospital-acquired infections. A retrospective study was done to determine the incidence of CAUTI in the Intensive Care Unit/High Dependency (ICU/HD) in Ng Teng Fong General Hospital (NTFGH) since […]

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Vijo Poulose, Jansen Koh, Tay Tunn Ren, Wong Hang Siang, Ian Wee, Hannah Hsien Hwei, Kam Jia Wen

A randomized pilot study of parenteral glutamine supplementation in severe sepsis

Abstract Purpose: Glutamine depletion can occur in critically ill patients and parenteral glutamine supplementation can have beneficial effects on critically ill patients by preserving gut barrier and improving immune function. We wanted to examine the effect of glutamine supplementation in a cohort of severe sepsis patients admitted to a hospital in South East Asia. Design: […]

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Rujipat Samransamruajkit, Kantara Saelim, Sumalee Hantragool, Jitladda Deerojanawong, Suchada Sritippayawan, Nuanchan Prapphal

A comparison of NSS vs balanced salt solution as a fluid resuscitation and impact of fluid balance on clinical outcomes in pediatric septic shock

Abstract Septic shock is a common condition affecting children worldwide. Initial resuscitation with crystalloid fluid is the first step in treatment of septic shock. However, there is increasing concern about side effects of using normal saline. Our objective was to compare the effectiveness of balanced salt solution vs 0.9% normal saline solution (NSS) on decreasing […]

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Omar Alberto Venegas Gurrola, Omar Uriel Sánchez Alba, María Isabel Solís Gamboa, Goretti Monserrat Rodríguez Delgado

A 20-year-old woman with spinal cord injury without radiological abnormalities (SCIWORA)

Abstract Spinal cord injury without radiological abnormalities (SCIWORA) has been defined as a direct trauma to the spinal cord, with no radiological or tomographic abnormalities, although there is a deficit, whether motor, sensory or both. (1) To establish the final diagnosis, shock, obstetrical complications, penetrating trauma to the spine and congenital malformations should be excluded. […]

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Tadashi Kaneko, Keiji Uezono, Ryuichi Karashima, Shinsuke Iwashita, Hiroki Irie, Shunji Kasaoka

Factors contributing to the accuracy of initial screening values measured by noninvasive spectrophotometric hemoglobin monitoring in an Emergency Department

Abstract Objective: Spectrophotometric hemoglobin (SpHb) monitoring is a new noninvasive technology for measuring hemoglobin (Hb). However, few studies have assessed the usefulness of the initial screening SpHb values, especially when measured in an Emergency Department. In this study, we examined the correlation between the initial screening SpHb values and laboratory-measured hemoglobin (Hb) concentrations. Design: This […]

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Ying Tung Sia, Pierre Laurencelle

Portal venous gas entrapment secondary to mesenteric ischemia after withdrawal of intra-aortic balloon pump: A case report with a rare ultrasound image

Abstract After coronary artery bypass graft (CABG), mesenteric ischemia is a rare but dreadful complication with high mortality rates. Prophylactic use of intra-aortic balloon pump (IABP) is a common practice in patients with severe coronary artery disease awaiting CABG. During withdrawal of the IABP, there is a risk of dislodging atheromatous debris, thus causing peripheral […]

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Saw Kian Cheah, Raha Abdul Rahman, Aliza Mohamad Yusof, Shereen Suet Ping Tang, Kamal-Bashar Abu Bakar

A fatal case of cerebral oedema and myocarditis associated with secondary dengue infection

Abstract Background: Secondary dengue infection (SDI), in the form of two sequential infections by different serotypes, will lead to severe dengue. Concomitant organ failure in particular cardiovascular (CVS) and central nervous system (CNS) carries further rise in the mortality rate. Case report: We report a confirmed SDI in a 27-year-old man who presented with hypovolemic […]

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Alexander N. Osipenko, Alexei V. Marochkov

Blood plasma plasmalogens and fatty acids in multiple organ dysfunction syndrome

Abstract Introduction: Changes in fatty acid composition as well as in a level of blood plasma plasmalogens in cases of various pathological conditions are evidences of lipid metabolism disorders and can indicate their reasons and degree. The objective of this study was to analyze fatty acids and plasmalogens of blood plasma in patients with multiple […]

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