Saw Kian Cheah, Raha Abdul Rahman, Aliza Mohamad Yusof, Shereen Suet Ping Tang, Kamal-Bashar Abu Bakar

A fatal case of cerebral oedema and myocarditis associated with secondary dengue infection

Abstract Background: Secondary dengue infection (SDI), in the form of two sequential infections by different serotypes, will lead to severe dengue. Concomitant organ failure in particular cardiovascular (CVS) and central nervous system (CNS) carries further rise in the mortality rate. Case report: We report a confirmed SDI in a 27-year-old man who presented with hypovolemic […]

Alexander N. Osipenko, Alexei V. Marochkov

Blood plasma plasmalogens and fatty acids in multiple organ dysfunction syndrome

Abstract Introduction: Changes in fatty acid composition as well as in a level of blood plasma plasmalogens in cases of various pathological conditions are evidences of lipid metabolism disorders and can indicate their reasons and degree. The objective of this study was to analyze fatty acids and plasmalogens of blood plasma in patients with multiple […]

Dewi Yulianti Bisri, Zafrulah Arifin, Ike Sri Redjeki, Heni Listianto, Tatang Bisri

The effect of selective COX-2 inhibitor on blood glutamate in moderate traumatic brain injury

Abstract Head injury is the leading cause of death and disability in adolescence, children and the elderly. Post-traumatic brain damage is determined by combination of primary and secondary head injuries. Neuroinflammation is one mechanism of secondary brain injury. Selective cyclooxygenase (sCOX-2) inhibitors are drugs commonly used in treatment of postoperative pain but also possess an […]

Suryadi Nicolaas Napoleon Tatura, Priscilla Kalensang, Jose Meky Mandei, Sitti Wahyuni, Irawan Yusuf, Dasril Daud

Albumin level as a predictor of shock and recurrent shock in children with dengue hemorrhagic fever

Abstract Background: The severity of dengue hemorrhagic fever (DHF) can be seen from bleeding and plasma leakage manifestations. Albumin level is one of the markers of plasma leakage in dengue infection. Whether albumin can be used as a predictor of shock in DHF patients or of recurrent shock in dengue shock syndrome (DSS) patients still […]

Alberto Leguina-Ruzzi, Marcial Cariqueo, Ricardo Gálvez

Three years after the REDOXS study: What we have learned in the use of glutamine in ICU patients?

Abstract Critical illness has been associated with glutamine (Gln) plasma levels depletion and its supplementation is related with better outcomes. In 2013 the Reducing Deaths due to Oxidative Stress (REDOXS) study, showed that the supplementation of Gln to total parenteral nutrition was associated with higher mortality without conferring beneficial effects. These conclusions had a high […]

Stephanie Bustamante-Mata, Alamgir A. Khan, Joseph Varon, Salim Surani

Ureteral stents, sepsis and acute kidney injury: Iatrogenic imperfecta!

Case presentation A 62-year-old woman with a past history of placement of bilateral ureteral “JJ” stents, presented to the hospital complaining of fever, chills, abdominal pain, oliguria and was found to be hypotensive. She was admitted to the intensive care unit (ICU), with the diagnosis of sepsis secondary to a urinary source. Her white blood […]

Emmanuel Urquieta, Humayun Anjum, Sheila Zanoria, Joseph Varon, Salim Surani

Mediastinal lipoma with vascular compression

Case description A 56-year-old gentleman presented to the emergency department with shortness of breath and neck swelling of a couple of weeks duration. After a comprehensive physical examination and chest radiograph revealing an upper mediastinal abnormality, a computed tomography (CT) scan of the chest (Figures 1A and 1B) depicted a 8x7x5.7 cm mass with homogenous […]

Stella Kawilarang, Ketut Surya Negara

Characteristics of the obstetric patients admitted to the Intensive Care Unit of Sanglah General Hospital in 2013-2016

Abstract Background: High risk pregnancy and complication during pregnancy or labor may need multidisciplinary management in the Intensive Care Unit (ICU). This study shows the characteristics of obstetric patients who were admitted to the ICU of Sanglah General Hospital Denpasar, Bali, Indonesia in 2013 to 2016. Objective: Our study was performed to provide database in […]

Daisy Suriadji, Dyah Kanya Wati, I Gusti Lanang Sidiartha, Ida Bagus Suparyatha, I Nyoman Budi Hartawan

Prevalence and association of cost and hospital malnutrition in Pediatric Intensive Care Unit Sanglah Hospital during 2015

Abstract Background: Early nutritional screening and adequate enteral nutrition for critically ill patients, started 24 hours after admission in pediatric intensive care unit (PICU) are accepted to improve health outcomes. Malnutrition prior to admission worsens the prognosis of severely ill children and it will lead to a higher mortality, a longer length of stay, and […]

Amit Kansal, Faheem Ahmed Khan, Muhammad Habibullah Rana

“Complete” loss of brain stem reflexes – not always brain death! Beware of amitriptyline overdose

Abstract We present a case of “complete” loss of brain stem reflexes following amitriptyline overdose, which mimicked brain death. This case highlights the complexities associated with clinical brain death determination and calls for close attention to details. Based on previously published case reports, we analyse the relationship with the amitriptyline dose, blood level and timing […]

Kelly Dewey, Michael Simmons, Fernanda Duarte, Salim Surani

Levamisole tainted cocaine induced vasculitis

Abstract Levamisole has been implicated in the vasculitis and aganulocytosis. It has been pulled from the United States market for human use. Due to its euphoric and bulking properties, it has been used as a bulking agent in cocaine. We hereby present a case of a 56-year-old Hispanic male, who developed vasculitis due to cocaine […]

Iqbal Ratnani, Faraya Bokhari, Rahim Hirani, Joseph Varon, Salim Surani

Peripherally-inserted central catheters: Watch for retained wires!

An increasing number of patients are being admitted to critical care units with multiple chronic medical conditions. In some of these patients, intravenous access is a challenge. With a concern for indwelling catheter infections, peripherally inserted central catheters (PICC). These lines have been advocated due to their lower rate of complications and comfort to the […]

Najeh Baccouche, Mabrouk Bahloul, Sabrine Bradai, Kais Regaieg, Fatma Ayedi, Mounir Bouaziz

Prognostic value of serum cholinesterase activity in the septic shock due to bacterial infections

Abstract Context: Kinetics of SChE activity analyses, in our knowledge, was not previously studied in the prediction of prognosis of patients with septic shock. Objective: We aimed to analyse kinetics of SChE activity in 4 patients with septic shock. Materials and methods: Prospective study. Results: The kinetics analyses of SChE activity showed that SChE activity […]

I Made Darma Yuda, Dyah Kanya Wati, I Nyoman Budi Hartawan, Ida Bagus Suparyatha

The association between delta shock index and mortality in children with shock

Abstract Background: Shock remains one leading cause of morbidity and mortality in hospitalized children. Delta shock index is a simple tool to assess and evaluate shock. Objective: To investigate whether delta shock index might be related to mortality in children with shock. Methods: Prospective cohort study. Setting: Emergency Room (ER) and Pediatric Intensive Care Unit […]

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