Therapeutic hypothermia in the year 2010: it is about time!

The use of therapeutic hypothermia (TH) in clinical medicine is no longer a rarity. Since the modern inception of this technique by Fay in the 1940s, TH has been used for a variety of clinical scenarios. (1,2) TH has gained significant popularity as a brain-protection strategy in victims of sudden cardiac death in whom return of spontaneous circulation (ROSC) has been obtained with coma. (3) Nonetheless, many trials and case series have shown the advantageous effects of lowering the body’s core temperature in a variety of other clinical conditions including near-drowning, hypoxemic brain injury, traumatic brain injury, traumatic cardiac arrest,