The Surviving sepsis campaign

The incidence of severe sepsis (sepsis with organ dysfunction) is increasing [1]. Several recent published studies have demonstrated decreased mortality and morbidity as a result of interventions and therapeutics applied to patients with sepsis [2-5]. These new data, resulting from rigorously performed, randomized controlled trials, combined with previous data for beneficial interventions not specific to sepsis management [6-10], such as DVT and stress ulcer prophylaxis, lend significant weight to the belief that critical care clinicians can now significantly reduce mortality in patients with severe sepsis and septic shock.