Case report: methylene blue for cardiogenic shock

Cardiogenic shock is the primary cause of death in hospitalized patients with acute myocardial infarction, particularly when left ventricle failure occurs. The best management of shock secondary to right or left ventricle failure is reestablishing blood flow in the infarct-related artery. (1) Despite quick treatment, cardiogenic shock causes 50% of deaths within the first 24 hour of the event. (2) A new paradigm for cardiogenic shock assumes that the pathophysiology of the disease includes the participation of guanylate cyclase, leading to the production of nitric oxide that contributes to the vasodilation and the poor response to vasopressors of some patients with this complication. (2)